Your Guide to Understanding Terpenes

Your Guide to Understanding Terpenes

When considering what kind of Hemp to choose to relax, de-stress, or reduce any pain or tension you might experience, you may have run across discussions about the role of terpenes.  While THC and Hemp tend to get the most airtime in the cannabis community, terpenes are also important naturally occurring compounds found in hemp plants. There are over 20,000 known terpenes in the plant kingdom. Currently, around 80 to 120 terpenes are found in different hemp varieties, with more being studied and discovered all the time.  Terpenes play an important role in wellness on their own, but in Hemp, they can offer the additional benefit of something called the “entourage effect.”  Terpenes may amplify the effects of Hemp within the body’s own endocannabinoid system and help Hemp get to work. 

What Are Terpenes? 

“What is a terpene?” “What are terpenes?” “What do terpenes do?” “Are terpenes weed?”  As a lesser-discussed botanical element, terpenes can generate a lot of confusion, especially when it comes to Hemp. However, terpenes are found in and produced by almost all plants, not just in hemp.  Terpenes are the organic compounds that give plants their scent, smell, and many of their medicinal properties. You may be familiar with terpenes from using essential oils, scented candles, naturally flavored foods, or more. For instance, if you’ve ever smelled a jasmine flower, peeled orange, or a pine-scented car freshener, you’ve already made good use of terpenes.  Plants produce terpenes as a part of their immune systems. They protect plants against harsh weather and work to keep off invasive insects, bacteria, and fungi. Terpenes are widely praised for their antibacterial, anti-inflammatory, and sometimes antiviral properties. Terpenes help plants, but they also have positive impacts on humans and animals. While terpenes are not psychoactive in the way THC is, many of these compounds affect the body and mind and are considered bioactive. Some terpenes, such as curcumin, naturally occurring in turmeric, have long been used in traditional medicine as an anti-inflammatory. Like the phytoncides found in conifer trees, others have beneficial effects on the lungs and mind, as studies of Japanese forest bathing have shown.  Terpenes are not exclusive to specific plants. Different herbs, spices, and plants will often share strains of terpenes that give them similar scents or properties. For instance, linalool, a terpene that gives lavender its distinctive soothing fragrance, is also found in some varieties of cannabis, as well as sweet basil, sweet orange, and bay leaves. Linalool is even used as an additive in some cleaning and beauty products because of its de-stressing and lightly insecticidal qualities. 

Cannabis Terpenes

When you think of terpenes in weed or hemp, you might think of different strains of the cannabis plant. However, all hemp plants have terpenes. Terpene distribution does not necessarily depend on Sativa leaf or Indica varieties.  Terpenes are produced within the hemp plant using specialized hairs, called trichomes. Trichomes are located on both the stems and leaves of the plant and usually run along the surface. They are responsible for creating the plant’s resin and give cannabis its distinctive musky odor and flavor. Some of the factors that influence the development of different terpenes in cannabis are:
  • Harvest time
  • Climate
  • Soil
  • Age of the plant

Terpenes Chart

Because there are around 120 currently known terpenes in hemp plants, with more still being discovered, creating a complete list of terpenes is a complex undertaking. However, using a terpene chart can help growers and buyers identify certain strains, and decide which will have the best effects for them. Additionally, finding Hemp with a high terpenes-to-cannabis ratio may be more effective than selecting a Hemp isolate. 

Terpenes Cannabinoids

Terpenes Cannabinoids You may be wondering why all the fuss about terpenes when what you’re searching for is the relief provided by Hemp, the other compound in hemp. However, research shows that whole-plant therapy may be the most effective way to absorb Hemp into the body. Terpenes play a valuable role in helping Hemp communicate with the body’s endocannabinoid system to provide maximum saturation, and thus maximum relief. This idea is known as the “entourage effect.”  Research has encouraged the use of broad or full-spectrum Hemp, meaning Hemp that retains its natural terpenes, as a way to best absorb the benefits of Hemp. Some full-spectrum Hemp oils even retain trace amounts of THC, though not enough to produce any psychoactive effects. Hemp use for mood disorders and epilepsy shows that using full-spectrum Hemp may allow the total benefits of Hemp to react within the body and brain. By contrast, Hemp isolate, the most refined version of Hemp, may not be as completely absorbed by the body and may not be as effective as taking a full-spectrum Hemp. 

Pure Relief Hemp

If you’re looking to take advantage of the natural terpenes in Hemp and want the benefits of a full-spectrum product, Pure Relief offers Hemp smokeables, edibles, oils, and tinctures. All Pure Relief products are cultivated from U.S.-grown plants and are lab tested for quality and purity.  Pure Relief Hemp oils are available in different strengths, sizes, and flavors, so you can select the experience that’s best for you. Even the lightest concentration oil, at 17 mg of Hemp per dose, still offers the full benefits of cannabis terpenes within every drop. Pure Relief products make use of this natural synergy, delivering a Hemp experience that provides the benefit of the entire plant. 


Many terpenes support wellness, promote relaxation, and ease inflammation. Cannabis terpenes are known for the additional benefit of contributing to the entourage effect, allowing Hemp to interact most effectively within the body’s endocannabinoid system.  For full-spectrum Hemp products that naturally deliver the complete benefits of the plant, Pure Relief offers a wide variety of oils, tinctures, smokeables, and edibles to help you get the relief you seek.
June 23, 2021 — admin
Tags: hemp Hemp Info
5 Things You Shouldn't Take With Hemp

5 Things You Shouldn't Take With Hemp

Cannabis is a complex plant packed with compounds and over 100 different cannabinoids. The limited research covering cannabidiol or Hemp, one of the most abundant cannabinoids found in the plant, shows evidence of a range of potential health benefits. We can use Hemp oil for epilepsy, chronic pain, stress, insomnia, and other medical conditions. As Hemp grows more popular, people are starting to ask the big question: "How will Hemp interact with my current medication setup?" Currently, limited research hints that Hemp can indeed have problematic interactions with some prescription drugs. The findings are far from definitive — more research on Hemp's interaction with different medications is still needed to better understand the situation.  Many doctors and scientists urge people taking Hemp (medically or recreationally) to be careful when mixing it with other prescriptions and to ask their doctor about potential interactions.

Hemp Interaction With Medication

Are you familiar with the grapefruit test? Many prescription medications will bear grapefruit warnings on the package, advising against eating the citrus fruit while taking the drug.  Most medications are broken down in the small intestine and the liver by a group of proteins called cytochrome P450 enzymes (CYPs). Through this process, the medication's benefits are delivered to the intended destination.  Grapefruit meddles with this activity and slows the breakdown process. The fruit also enhances the side effects and duration of the drug in a person's system.  One 2013 study revealed that grapefruit could increase blood content levels when mixed with at least 80 different medications. The reported results were critical, including organ failure, irregular heartbeat, internal bleeding, and even death.  The quality, variety, and purity of Hemp all play a part in how it will interact with your body and your medication. Furthermore, the timing of when the Hemp is taken along with any other drug will tell how they interact in your body. And of course, because every individual is different and reacts to medications differently, depending on age, weight, and other factors, your experience might be different. Let's explore the current research on Hemp's interaction with some of the most common over-the-counter medications. 

What Drugs Should Not Be Taken With Hemp

What Drugs Should Not Be Taken With CBD

Hemp and Ibuprofen

Ibuprofen is an anti-inflammatory medicine (NSAID) that subdues pain as well as inflammation in the body. Because ibuprofen has a risk of blood-thinning, it can cause shortness of breath, dizziness, and nausea. Potentially, Hemp may extend the duration and concentration of ibuprofen in the body, thereby increasing the intensity of the side effects.  While no human studies to date cover Hemp's interaction with NSAIDs specifically, two studies conducted on rodents in 2006 and 2008 suggest that other cannabinoids (not Hemp) may work in tandem with NSAIDs like ibuprofen to intensify the pain-reducing effect

Hemp and Warfarin

Warfarin (Coumadin) is an anticoagulant (blood thinner) drug used to stop the development of fatal blood clots that could lead to heart attacks or strokes. Warfarin's side effects include bleeding, severe headaches, swelling, or pain in extremities. A study published in Epilepsy & Behavior Case Reports revealed that Hemp enhances the effects of blood-thinning drugs by slowing down how the body metabolizes the medication and thereby extending its presence in the body. By prolonging the duration of warfarin in the body, Hemp could potentially worsen some of the adverse side effects. 

Hemp and Metoprolol

Metoprolol is a beta-blocker taken to manage high blood pressure by reducing the heart rate and adjusting the discharge of epinephrine, the hormone linked to stress, and other processes. Yes, beta-blockers reduce blood pressure but sometimes produce adverse side effects, such as nausea, dizziness, heartburn, stomach pain, and cold hands and feet. While no current published studies cover the potential interactions between Hemp and metoprolol, some placebo-controlled research has linked Hemp with lowered blood pressure when taken individually. For people taking metoprolol, the combination with Hemp could have adverse consequences on blood pressure. 

Hemp and Metformin

Metformin is a prescribed medication for type 2 diabetes to help manage blood sugar levels. Side effects of metformin range from low blood sugar and nausea to diarrhea and vomiting. While one 2006 study showed that Hemp oil reduced the incidence of diabetes in some animals, very little research has explicitly covered Hemp as a potential treatment for diabetes or the compound's interactions with the Metformin. More research is still needed on Hemp's interaction with diabetes and Metformin. Patients taking Metformin should talk to their physician before incorporating Hemp in their diet.

Hemp and Plavix

Plavix, better known by its brand name clopidogrel, is commonly prescribed for people suffering from or are prone to have a heart attack. The drug works by preventing blood platelets from developing clots in arteries near the heart. According to a 2011 study, it is possible that Hemp may produce an inhibitory effect on the protein that metabolizes Plavix. This could cause Plavix to linger longer in the system and minimize the intended results. Further research is needed to conclude whether Hemp could lower Plavix's effectiveness in stopping heart attacks. 

Can Caffeine Counteract Hemp?

Can Caffeine Counteract CBD? Hemp and caffeine are both growing in popularity, especially when infused. Many people rely on caffeine for its energy boost and to help them stay awake. You'd think that when mixed with Hemp, it would counteract the desired effects. Surprisingly, a 2007 study on rodents showed that caffeine is metabolized by CYP enzymes, which Hemp represses. This could lead to an extension of caffeine’s duration in the body and could potentially extend the stimulating effects of caffeine as well.


Hemp’s safety profile is grounded in research, confirming that it is well-tolerated and safe to use. Hemp is a complex compound that has a penetrating impact on a wide variety of bodily systems, making it such an efficient therapeutic alternative for so many common conditions.  At the same time, it is important to remember that Hemp may also interact with other drugs you're currently taking (not mentioned on this list). That's why Hemp should be administered with care and prudence.
November 11, 2020 — admin